Recombinant Human S100A11, None tagged

• Cat.No.: S100A11-3102H
• Product Overview: Recombinant Human S100A11 (NP_005611.1) native form (Met 1-Thr 105), fused with no tag, was produced in E. coli.

Specification

• Source: E. coli
• Species: Human
• Form: Lyophilized from sterile PBS, pH 7.4
• Molecular Mass: The recombinant human S100A11 consisting of 105 amino acids and migrates with an apparent molecular mass of 24 & 12 kDa corresponding to dimeric and monomeric form as estimated in SDS-PAGE under non-reduced condition.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: S100A11 S100 calcium binding protein A11 [ Homo sapiens ]
• Official Symbol: S100A11
• Gene ID: 6282
• mRNA Refseq: NM_005620
• Protein Refseq: NP_005611
• MIM: 603114
• UniProt ID: P31949

Reviews

03/09/2021

Quality product, delivered on time—perfect!

01/30/2019

Fantastic quality, hassle-free delivery!

10/16/2018

A+ for both product quality and excellent service!

Q&As

Can you elaborate on the role of S100A11 in cellular signaling pathways, particularly those involved in cancer progression and metastasis?

S100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.

How does S100A11 contribute to cellular differentiation, and are there specific target genes or pathways involved in this process?

S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.

How is S100A11 expression regulated, and what are the transcriptional and post-translational mechanisms influencing its activity?

S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.

In neurodegenerative diseases, is there evidence of S100A11 involvement, and what are the potential mechanisms linking this protein to neurological pathology?

Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.

What is S100A11, and what is its cellular localization and physiological role?

S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.