Recombinant Human SAE1, His-tagged
Cat.No. : | SAE1-29262TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 18-346 of Human SAE1 with N terminal His tag; 329 amino acids, Predicted Mwt 37kDa. |
- Specification
- Gene Information
- Related Products
Description : | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expression level increases during S phase and drops in G2 phase (at protein level). |
Form : | Lyophilised:Reconstitute with 135 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QYDRQIRLWGLEAQKRLRASRVLLV GLKGLGAEIAKNLIL AGVKGLTMLDHEQVTPEDPGAQFLI RTGSVGRNRAEAS LERAQNLNPMVDVKVDTEDIEKKPE SFFTQFDAVCLTCCS RDVIVKVDQICHKNSIKFFTGDVFG YHGYTFANLGEHE FVEEKTKVAKVSQGVEDGPDTKRAK LDSSETTMVKKKV VFCPVKEALEVDWSSEKAKAALKRT TSDYFLLQVLLKFRT DKGRDPSSDTYEEDSELLLQIRNDV LDSLGISPDLLPE DFVRYCFSEMAPVCAVVGGILAQEI VKALSQRDPPHNNFFFFDGMKGNGI VECLGPK |
Sequence Similarities : | Belongs to the ubiquitin-activating E1 family. |
Gene Name : | SAE1 SUMO1 activating enzyme subunit 1 [ Homo sapiens ] |
Official Symbol : | SAE1 |
Synonyms : | SAE1; SUMO1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; activator Of sumo 1; AOS1; FLJ3091; Sua1; |
Gene ID : | 10055 |
mRNA Refseq : | NM_001145713 |
Protein Refseq : | NP_001139185 |
MIM : | 613294 |
Uniprot ID : | Q9UBE0 |
Chromosome Location : | 19q13.32 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; |
Function : | ATP-dependent protein binding; contributes_to SUMO activating enzyme activity; enzyme activator activity; ligase activity; nucleotide binding; |
Products Types
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SAE1-1949H | Recombinant Human SAE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Lysates | ||
SAE1-001HCL | Recombinant Human SAE1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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