Recombinant Human SAR1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SAR1A-2134H
• Product Overview: SAR1A MS Standard C13 and N15-labeled recombinant protein (NP_001136120) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 22.4 kDa
• AA Sequence: MSFIFEWIYNGFSSVLQFLGLYKKS GKLVFLGLDNAGKTTLLHMLKDDRL GQHVPTLHPTSEELTIAGMTFTTFD LGGHEQARRVWKNYLPAINGIVFLV DCADHSRLVESKVELNALMTDETIS NVPILILGNKIDRTDAISEEKLREI FGLYGQTTGKGNVTLKELNARPMEV FMCSVLKRQGYGEGFRWLSQYIDTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SAR1A secretion associated Ras related GTPase 1A [ Homo sapiens (human) ]
• Official Symbol: SAR1A
• Synonyms: SAR1A; SAR1 homolog A (S. cerevisiae); SAR1a gene homolog (S. cerevisiae) 1, SAR1a gene homolog 1 (S. cerevisiae), SARA1; GTP-binding protein SAR1a; SAR1; Sara; SAR1 gene homolog A; SAR1a gene homolog 1; COPII-associated small GTPase; SARA1; masra2
• Gene ID: 56681
• mRNA Refseq: NM_001142648
• Protein Refseq: NP_001136120
• MIM: 607691
• UniProt ID: Q9NR31