| Description : |
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
58.8 kDa |
| AA Sequence : |
MSSSPWEPATLRRVFVVGVGMTKFV KPGAENSRDYPDLAEEAGKKALADA QIPYSAVDQACVGYVFGDSTCGQRA IYHSLGMTGIPIINVNNNCATGSTA LFMARQLIQGGVAECVLALGFEKMS KGSLGIKFSDRTIPTDKHVDLLINK YGLSAHPVAPQMFGYAGKEHMEKYG TKIEHFAKIGWKNHKHSVNNPYSQF QDEYSLDEVMASKEVFDFLTILQCC PTSDGAAAAILASEAFVQKYGLQSK AVEILAQEMMTDLPSSFEEKSIIKM VGFDMSKEAARKCYEKSGLTPNDID VIELHDCFSTNELLTYEALGLCPEG QGATLVDRGDNTYGGKWVINPSGGL ISKGHPLGATGLAQCAELCWQLRGE AGKRQVPGAKVALQHNLGIGGAVVV TLYKMGFPEAASSFRTHQIEAVPTS SASDGFKANLVFKEIEKKLEEEGEQ FVKKIGGIFAFKVKDGPGGKEATWV VDVKNGKGSVLPNSDKKADCTITMA DSDFLALMTGKMNPQSAFFQGKLKI TGNMGLAMKLQNLQLQPGNAKLTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
