| Description : |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
24.7 kDa |
| Protein Length : |
310 |
| AA Sequence : |
MRRAALWLWLCALALSLQPALPQIV ATNLPPEDQDGSGDDSDNFSGSGAG ALQDITLSQQTPSTWKDTQLLTAIP TSPEPTGLEATAASTSTLPAGEGPK EGEAVVLPEVEPGLTAREQEATPRP RETTQLPTTHLASTTTATTAQEPAT SHPHRDMQPGHHETSTPAGPSQADL HTPHTEDGGPSATERAAEDGASSQL PAAEGSGEQDFTFETSGENTAVVAV EPDRRNQSPVDQGATGASQGLLDRK EVLGGVIAGGLVGLIFAVCLVGFML YRMKKKDEGSYSLEEPKQANGGAYQ KPTKQEEFYA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
