Description : |
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : |
E. coli |
Species : |
Human |
Tag : |
His-SUMO |
Form : |
Tris-based buffer, 50% glycerol. |
Molecular Mass : |
84.0 kDa |
AA Sequence : |
SAKVSDSISAQYPVVDHEFDAVVVG AGGAGLRAAFGLSEAGFNTACVTKL FPTRSHTVAAQGGINAALGNMEEDN WRWHFYDTVKGSDWLGDQDAIHYMT EQAPAAVVELENYGMPFSRTEDGKI YQRAFGGQSLKFGKGGQAHRCCCVA DRTGHSLLHTLYGRSLRYDTSYFVE YFALDLLMENGECRGVIALCIEDGS IHRIRAKNTVVATGGYGRTYFSCTS AHTSTGDGTAMITRAGLPCQDLEFV QFHPTGIYGAGCLITEGCRGEGGIL INSQGERFMERYAPVAKDLASRDVV SRSMTLEIREGRGCGPEKDHVYLQL HHLPPEQLATRLPGISETAMIFAGV DVTKEPIPVLPTVHYNMGGIPTNYK GQVLRHVNGQDQIVPGLYACGEAAC ASVHGANRLGANSLLDLVVFGRACA LSIEESCRPGDKVPPIKPNAGEESV MNLDKLRFADGSIRTSELRLSMQKS MQNHAAVFRVGSVLQEGCGKISKLY GDLKHLKTFDRGMVWNTDLVETLEL QNLMLCALQTIYGAEARKESRGAHA REDYKVRIDEYDYSKPIQGQQKKPF EEHWRKHTLSYVDVGTGKVTLEYRP VIDKTLNEADCATVPPAIRSY |
Purity : |
Greater than 90% as determined by SDS-PAGE. |
Storage : |
The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |