Recombinant Human SDR16C5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SDR16C5-1709H
• Product Overview: SDR16C5 MS Standard C13 and N15-labeled recombinant protein (NP_620419) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.1 kDa
• AA Sequence: MSFNLQSSKKLFIFLGKSLFSLLEA MIFALLPKPRKNVAGEIVLITGAGS GLGRLLALQFARLGSVLVLWDINKE GNEETCKMAREAGATRVHAYTCDCS QKEGVYRVADQVKKEVGDVSILINN AGIVTGKKFLDCPDELMEKSFDVNF KAHLWTYKAFLPAMIANDHGHLVCI SSSAGLSGVNGLADYCASKFAAFGF AESVFVETFVQKQKGIKTTIVCPFF IKTGMFEGCTTGCPSLLPILEPKYA VEKIVEAILQEKMYLYMPKLLYFMM FLKSFLPLKTGLLIADYLGILHAMD GFVDQKKKLTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SDR16C5 short chain dehydrogenase/reductase family 16C member 5 [ Homo sapiens (human) ]
• Official Symbol: SDR16C5
• Synonyms: SDR16C5; short chain dehydrogenase/reductase family 16C, member 5; epidermal retinol dehydrogenase 2; RDH E2; RDHE2; EPHD-2; retSDR2; epidermal retinal dehydrogenase 2; retinal short chain dehydrogenase reductase; retinal short-chain dehydrogenase reductase 2; short-chain dehydrogenase/reductase family 16C member 5; RDH#2; RDH-E2; FLJ33105
• Gene ID: 195814
• mRNA Refseq: NM_138969
• Protein Refseq: NP_620419
• MIM: 608989
• UniProt ID: Q8N3Y7