| Description : |
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
81.8 kDa+Y1AO5V1:AC54 |
| Protein Length : |
830 |
| AA Sequence : |
MANCQIAILYQRFQRVVFGISQLLC FSALISELTNQKEVAAWTYHYSTKA YSWNISRKYCQNRYTDLVAIQNKNE IDYLNKVLPYYSSYYWIGIRKNNKT WTWVGTKKALTNEAENWADNEPNNK RNNEDCVEIYIKSPSAPGKWNDEHC LKKKHALCYTASCQDMSCSKQGECL ETIGNYTCSCYPGFYGPECEYVREC GELELPQHVLMNCSHPLGNFSFNSQ CSFHCTDGYQVNGPSKLECLASGIW TNKPPQCLAAQCPPLKIPERGNMTC LHSAKAFQHQSSCSFSCEEGFALVG PEVVQCTASGVWTAPAPVCKAVQCQ HLEAPSEGTMDCVHPLTAFAYGSSC KFECQPGYRVRGLDMLRCIDSGHWS APLPTCEAISCEPLESPVHGSMDCS PSLRAFQYDTNCSFRCAEGFMLRGA DIVRCDNLGQWTAPAPVCQALQCQD LPVPNEARVNCSHPFGAFRYQSVCS FTCNEGLLLVGASVLQCLATGNWNS VPPECQAIPCTPLLSPQNGTMTCVQ PLGSSSYKSTCQFICDEGYSLSGPE RLDCTRSGRWTDSPPMCEAIKCPEL FAPEQGSLDCSDTRGEFNVGSTCHF SCDNGFKLEGPNNVECTTSGRWSAT PPTCKGIASLPTPGLQCPALTTPGQ GTMYCRHHPGTFGFNTTCYFGCNAG FTLIGDSTLSCRPSGQWTAVTPACR AVKCSELHVNKPIAMNCSNLWGNFS YGSICSFHCLEGQLLNGSAQTACQE NGHWSTTVPTCQAGPLTIQEALTYF GGAVASTIGLIMGGTLLALLRKRFR QKDDGKCPLNPHSHLGTYGVFTNAA FDPSP |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
