Recombinant Human SERPINA3 Protein, His-tagged

• Cat.No.: SERPINA3-571H
• Product Overview: Recombinant human SERPINA3 protein with His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 46.6 kDa
• Protein Length: 423
• AA Sequence: MERMLPLLALGLLAAGFCPAVLCHP NSPLDEENLTQENQDRGTHVDLGLA SANVDFAFSLYKQLVLKAPDKNVIF SPLSISTALAFLSLGAHNTTLTEIL KGLKFNLTETSEAEIHQSFQHLLRT LNQSSDELQLSMGNAMFVKEQLSLL DRFTEDAKRLYGSEAFATDFQDSAA AKKLINDYVKNGTRGKITDLIKDLD SQTMMVLVNYIFFKAKWEMPFDPQD THQSRFYLSKKKWVMVPMMSLHHLT IPYFRDEELSCTVVELKYTGNASAL FILPDQDKMEEVEAMLLPETLKRWR DSLEFREIGELYLPKFSISRDYNLN DILLQLGIEEAFTSKADLSGITGAR NLAVSQVVHKAVLDVFEEGTEASAA TAVKITLLSALVETRTIVRFNRPFL MIIVPTDTQNIFFMSKVTNPKQA
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens (human) ]
• Official Symbol: SERPINA3
• Synonyms: SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin; ACT; alpha 1 antichymotrypsin; serpin A3; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3; AACT; GIG24; GIG25; MGC88254
• Gene ID: 12
• mRNA Refseq: NM_001085
• Protein Refseq: NP_001076
• MIM: 107280
• UniProt ID: P01011