"SETD6" Related Products

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Recombinant Human SETD6 protein, GST-tagged

Cat.No.: SETD6-261H
Product Overview: Recombinant Human SETD6(1-473 aa) fused with GST tag at N-terminal was expressed in E. coli.
Description: SETD6 is a SET-domain containing protein lysine methyltransferase, catalyzing the mono-methylation of RelA (p65, NFkB3) at lysine 310. Methylation of RelA attenuates RelA-dependant transcriptional pathways, including inflammatory responses in primary immune cells. SETD6 is downregulated in a diseases of hyper inflammation.
Source: E. coli
Species: Human
Tag : GST
Form: 100 mM Tris pH 8.0, 10mM glutathione and 25% glycerol.
Molecular Mass: 72 kDa
Applications: Recombinant SETD6, human is useful for RelA/p65 methylation experiments, enzyme kinetics and inhibitor screening. Use of 2-5 µg SETD6 per reaction with 1 µg recombinant RelA as a substrate is recommended.
Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration: 2.2 µg/µl
Gene Name: SETD6 SET domain containing 6 [ Homo sapiens ]
Official Symbol: SETD6
Synonyms: SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6;
Gene ID: 79918
mRNA Refseq: NM_001160305
Protein Refseq: NP_001153777
UniProt ID: Q8TBK2
Chromosome Location: 16q21

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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