Recombinant Human SETD7 Protein, His-tagged
Cat.No. : | SETD7-22H |
Product Overview : | Recombinant human SETD7(1-366) protein with a N-terminal His-tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 43.3 kDa |
Protein length : | 1-366 |
Purity : | ≥95% estimated by SDS-PAGE |
Stability : | ≥ 6 months |
Storage : | Store it at -80 centigrade |
Storage Buffer : | 50 mM HEPES, pH 7.2, 100 mM sodium chloride, and 20% glycerol |
Gene Name : | SETD7 SET domain containing 7, histone lysine methyltransferase [ Homo sapiens (human) ] |
Official Symbol : | SETD7 |
Synonyms : | SETD7; SET domain containing 7, histone lysine methyltransferase; KMT7; SET7; SET9; SET7/9; histone-lysine N-methyltransferase SETD7; H3-K4-HMTase SETD7; SET domain containing 7, lysine methyltransferase; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; lysine N-methyltransferase 7 |
Gene ID : | 80854 |
mRNA Refseq : | NM_001306199 |
Protein Refseq : | NP_001293128 |
MIM : | 606594 |
UniProt ID : | Q8WTS6 |
Products Types
◆ Recombinant Protein | ||
SETD7-3983R | Recombinant Rhesus Macaque SETD7 Protein, His (Fc)-Avi-tagged | +Inquiry |
SETD7-8071M | Recombinant Mouse SETD7 Protein, His (Fc)-Avi-tagged | +Inquiry |
SETD7-89H | Recombinant Human SET Domain-Containing Protein 7 | +Inquiry |
SETD7-129H | Active Recombinant Human SETD7 Protein, His-tagged | +Inquiry |
Setd7-5801M | Recombinant Mouse Setd7 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SETD7-1925HCL | Recombinant Human SETD7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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