Recombinant Human SFRS Protein Kinase 2, GST-tagged, Active
Cat.No. : | SRPK2-436H |
Product Overview : | Recombinant full-length human SRPK2 was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 135 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SRPK2-436H |
Description : | SRPK2 is a member of the serine/arginine (SR) protein-specific kinase family that are cell cycle-regulated protein kinases which phosphorylate SR domain-containing proteins in nuclear speckles and mediate the pre-mRNA splicing events. SRPK2 knock down results in hypophosphorylation of the serine/arginine domain-containing human PRP28 protein thereby destabilizing PRP28 association with the tri-snRNP. RNAi-mediated depletion in HeLa cells showed that SRPK2 is essential for cell viability, and it is required for spliceosomal B complex formation. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | SRPK2 SFRS protein kinase 2 [ Homo sapiens ] |
Synonyms : | SRPK2; SFRS protein kinase 2; SFRSK2; FLJ36101; serine/arginine-rich protein-specific kinase 2; H_RG152G17.1a; H_RG152G17.1b; WUGSC:H_RG152G17.1a; serine kinase SRPK2; EC 2.7.11.1; SR-protein-specific kinase 2; Serine/threonine-protein kinase SRPK2 |
Gene ID : | 6733 |
mRNA Refseq : | NM_182691 |
Protein Refseq : | NP_872633 |
MIM : | 602980 |
UniProt ID : | P78362 |
Chromosome Location : | 7q22-q31.1 |
Function : | ATP binding; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
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SRPK2-1069H | Recombinant Human SRPK2 Protein (S2-N688), Tag Free | +Inquiry |
SRPK2-1068H | Recombinant Human SRPK2 Protein (S2-N688), GST tagged | +Inquiry |
Srpk2-6131M | Recombinant Mouse Srpk2 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SRPK2-1474HCL | Recombinant Human SRPK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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