Recombinant Human SGSH protein, His-tagged
Cat.No. : | SGSH-195H |
Product Overview : | Recombinant Human SGSH fused with His tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Supplied as a 0.2 µM filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol,pH7.5 |
Molecular Mass : | 55.72kD |
AA Sequence : | RPRNALLLLADDGGFESGAYNNSAI ATPHLDALARRSLLFRNAFTSVSSC SPSRASLLTGLPQHQNGMYGLHQDV HHFNSFDKVRSLPLLLSQAGVRTGI IGKKHVGPETVYPFDFAYTEENGSV LQVGRNITRIKLLVRKFLQTQDDRP FFLYVAFHDPHRCGHSQPQYGTFCE KFGNGESGMGRIPDWTPQAYDPLDV LVPYFVPNTPAARADLAAQYTTVGR MDQGVGLVLQELRDAGVLNDTLVIF TSDNGIPFPSGRTNLYWPGTAEPLL VSSPEHPKRWGQVSEAYVSLLDLTP TILDWFSIPYPSYAIFGSKTIHLTG RSLLPALEAEPLWATVFGSQSHHEV TMSYPMRSVQHRHFRLVHNLNFKMP FPIDQDFYVSPTFQDLLNRTTAGQP TGWYKDLRHYYYRARWELYDRSRDP HETQNLATDPRFAQLLEMLRDQLAK WQWETHDPWVCAPDGVLEEKLSPQC QPLHNELVDHHHHHH |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Gene Name : | SGSH N-sulfoglucosamine sulfohydrolase [ Homo sapiens ] |
Official Symbol : | SGSH |
Synonyms : | SGSH; N-sulfoglucosamine sulfohydrolase; N-sulphoglucosamine sulphohydrolase; HSS; MPS3A; mucopolysaccharidosis type IIIA; SFMD; sulfamidase; sulphamidase; heparan sulfate sulfatase; sulfoglucosamine sulfamidase; |
Gene ID : | 6448 |
mRNA Refseq : | NM_000199 |
Protein Refseq : | NP_000190 |
MIM : | 605270 |
UniProt ID : | P51688 |
Chromosome Location : | 17q25.3 |
Pathway : | Glycosaminoglycan degradation, organism-specific biosystem; Glycosaminoglycan degradation, conserved biosystem; Heparan sulfate degradation, organism-specific biosystem; Heparan sulfate degradation, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | N-sulfoglucosamine sulfohydrolase activity; catalytic activity; hydrolase activity; metal ion binding; sulfuric ester hydrolase activity; |
Products Types
◆ Recombinant Protein | ||
SGSH-1998H | Recombinant Human SGSH Protein, His (Fc)-Avi-tagged | +Inquiry |
SGSH-695H | Recombinant Human SGSH Protein, His/GST-tagged | +Inquiry |
Sgsh-5829M | Recombinant Mouse Sgsh Protein, Myc/DDK-tagged | +Inquiry |
SGSH-22H | Active Recombinant Human SGSH protein, His-tagged | +Inquiry |
SGSH-6660Z | Recombinant Zebrafish SGSH | +Inquiry |
◆ Lysates | ||
SGSH-1884HCL | Recombinant Human SGSH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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