Recombinant Human SHPK Protein, GST-Tagged

• Cat.No.: SHPK-1329H
• Product Overview: Human CARKL full-length ORF (NP_037408.2, 1 a.a. - 478 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.9 kDa
• AA Sequence: MAARPITLGIDLGTTSVKAALLRAA PDDPSGFAVLASCARAARAEAAVES AVAGPQGREQDVSRILQALHECLAA LPRPQLRSVVGIGVSGQMHGVVFWK TGQGCEWTEGGITPVFEPRAVSHLV TWQDGRCSSEFLASLPQPKSHLSVA TGFGCATIFWLLKYRPEFLKSYDAA GTIHDYVVAMLCGLPRPLMSDQNAA SWGYFNTQSQSWNVETLRSSGFPVH LLPDIAEPGSVAGRTSHMWFEIPKG TQVGVALGDLQASVYSCMAQRTDAV LNISTSVQLAASMPSGFQPAQTPDP TAPVAYFPYFNRTYLGVAASLNGGN VLATFVHMLVQWMADLGLEVEESTV YSRMIQAAVQQRDTHLTITPTVLGE RHLPDQLASVTRISSSDLSLGHVTR ALCRGIVQNLHSMLPIQQLQEWGVE RVMGSGSALSRNDVLKQEVQRAFPL PMSFGQDVDAAVGAALVMLRRHLNQ KES
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: SHPK sedoheptulokinase [ Homo sapiens ]
• Official Symbol: SHPK
• Synonyms: SHPK; sedoheptulokinase; carbohydrate kinase like, CARKL; SHK; carbohydrate kinase-like protein; CARKL; FLJ32478
• Gene ID: 23729
• mRNA Refseq: NM_013276
• Protein Refseq: NP_037408
• MIM: 605060
• UniProt ID: Q9UHJ6