Recombinant Human SIGLEC15 Protein, Fc\Avi-tagged
Cat.No. : | SIGLEC15-185H |
Product Overview : | Biotinylated Recombinant Human Sialic Acid-binding Ig-like Lectin 15 is produced by our Mammalian expression system and the target gene encoding Phe20-Thr263 is expressed with a Fc, Avi tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Human Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO−-terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type Ig domains which have no binding activity. Siglecs differ in the number of these C2-type domains. Human Siglec-15 consists of a 244 amino acid (aa) extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 function is important for osteoclast formation and TRANCE/RANK Ligand signaling in osteoclasts. |
Source : | Human Cells |
Species : | Human |
Tag : | Fc\Avi |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, 150mM NaCl, 0.3% Chaps, 5% Trehalose, pH 7.4. |
AA Sequence : | Phe20-Thr263 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | SIGLEC15 sialic acid binding Ig like lectin 15 [ Homo sapiens (human) ] |
Official Symbol : | SIGLEC15 |
Synonyms : | Sialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3; HsT1361; SIGLEC-15 |
Gene ID : | 284266 |
mRNA Refseq : | NM_213602.3 |
Protein Refseq : | NP_998767.1 |
MIM : | 618105 |
UniProt ID : | Q6ZMC9 |
Products Types
◆ Recombinant Protein | ||
SIGLEC15-292H | Recombinant Active Human SIGLEC15 Protein (ECD), His-tagged(C-ter) | +Inquiry |
SIGLEC15-2057H | Recombinant Human SIGLEC15 Protein, His&GST-tagged | +Inquiry |
SIGLEC15-291H | Recombinant Active Human SIGLEC15 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
SIGLEC15-13H | Recombinant Human SIGLEC15 Protein, C-Fc-Avi tagged, Biotinylated | +Inquiry |
SIGLEC15-4058H | Recombinant Human SIGLEC15 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIGLEC15-1847HCL | Recombinant Human SIGLEC15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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