Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1, His-tagged
Cat.No. : | SIT1-6861H |
Product Overview : | Recombinant human SIT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 16.9 kDa. |
- Specification
- Gene Information
- Related Products
Description : | SIT1, also known as signaling threshold-regulating transmembrane adapter 1, negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. This protein involved in positive selection of T-cells. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol. |
Molecular Mass : | 16.9 kDa (156aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). |
Protein length : | 1-196aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MHLSQWTRGR SRSHPGQGRS GESVEEVPLY GNLHYLQTGR LSQDPEPDQQ DPTLGGPARA AEEVMCYTSL QLRPPQGRIP GPGTPVKYSE VVLDSEPKSQ ASGPEPELYA SVCAQTRRAR ASFPDQAYAN SQPAAS |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | SIT1 signaling threshold regulating transmembrane adaptor 1 [ Homo sapiens ] |
Official Symbol : | SIT1 |
Synonyms : | SIT1; signaling threshold regulating transmembrane adaptor 1; suppression inducing transmembrane adaptor 1; signaling threshold-regulating transmembrane adapter 1; SHP2 interacting transmembrane adaptor; SIT; gp30/40; suppression-inducing transmembrane adapter 1; SHP2-interacting transmembrane adapter protein; SHP2-interacting transmembrane adaptor protein; RP11-331F9.5; MGC125908; MGC125909; MGC125910; |
Gene ID : | 27240 |
mRNA Refseq : | NM_014450 |
Protein Refseq : | NP_055265 |
MIM : | 604964 |
UniProt ID : | Q9Y3P8 |
Chromosome Location : | 9p13-p12 |
Pathway : | T Cell Receptor Signaling Pathway, organism-specific biosystem; |
Function : | SH2 domain binding; kinase binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Sit1-693R | Recombinant Rat Sit1 Protein, His-tagged | +Inquiry |
SIT1-5070R | Recombinant Rat SIT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIT1-4024R | Recombinant Rhesus Macaque SIT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sit1-1230R | Recombinant Rat Sit1 Protein, His-tagged | +Inquiry |
Sit1-5887M | Recombinant Mouse Sit1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SIT1-1827HCL | Recombinant Human SIT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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