Recombinant Human SIRPA Protein, Fc-tagged
Cat.No. : | SIRPA-520H |
Product Overview : | Human SIRP alpha is expressed from mammalian with a Fc tag at the C-terminal. It contains Glu31-Arg370. |
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Description : | Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction." |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Protein length : | Glu31-Arg370 |
Endotoxin : | Less than 0.5 EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE. > 95% as determined by HPLC. |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | SIRPA signal regulatory protein alpha [ Homo sapiens (human) ] |
Official Symbol : | SIRPA |
Synonyms : | BIT; MFR; P84; SIRP; MYD-1; SHPS1; CD172A; PTPNS1 |
Gene ID : | 140885 |
mRNA Refseq : | NM_001040022.1 |
Protein Refseq : | NP_001035111.1 |
MIM : | 602461 |
UniProt ID : | P78324 |
Products Types
◆ Recombinant Protein | ||
SIRPA-5066R | Recombinant Rat SIRPA Protein, His (Fc)-Avi-tagged | +Inquiry |
Sirpa-5882M | Recombinant Mouse Sirpa Protein, Myc/DDK-tagged | +Inquiry |
SIRPA-3306H | Active Recombinant Human SIRPA protein(Met1-Arg369(S44L, S50T, I52T, H54R, V57A)), His-tagged | +Inquiry |
SIRPA-1372H | Recombinant Human SIRPA protein(Met1-Arg369), His-tagged, Biotinylated | +Inquiry |
SIRPA-019H | Recombinant Human SIRPA Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
SIRPA-1650MCL | Recombinant Mouse SIRPA cell lysate | +Inquiry |
SIRPA-1005RCL | Recombinant Rat SIRPA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewI am thankful for the immense support provided by this protein reagent for my experimental work!
This protein substance is truly an indispensable tool in my laboratory!
Its performance is stable and reliable, and the manufacturer's quality control ensures that every experiment runs smoothly.
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