Recombinant Human SIRPA protein, His-Avi-tagged
| Cat.No. : | SIRPA-324H |
| Product Overview : | Recombinant human Sirpa V8 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Glu31-Arg369. |
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| Description : | Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophagemediated destruction. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His-Avi |
| Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Molecular Mass : | The protein has a predicted MW of 40.1 kDa.Due to glycosylation, the protein migrates to 52-68 KDa based on Bis-Tris PAGE result. |
| Protein length : | Glu31-Arg369 |
| Endotoxin : | Less than 0.05 EU per ug by the LAL method. |
| Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
| Gene Name : | SIRPA |
| Official Symbol : | SIRPA |
| Synonyms : | CD172 antigen-like family member A; CD172a antigen; CD172a;BIT; BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs; Brain Ig-like molecule with tyrosine-based activation motifs; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MFR; MFRtyrosine phosphatase SHP substrate 1; MyD-1 antigen; MYD1; MYD-1; P84; protein tyrosine phosphatase, non-receptor type substrate 1; PTPNS1; SHP substrate 1; SHPS1; SHPS-1; SHPS1CD172A; signal-regulatory protein alpha; Signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP alpha; SIRPA; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; SIRPtyrosine-protein phosphatase non-receptor type substrate 1 |
| Gene ID : | 140885 |
| mRNA Refseq : | NM_001040022.1 |
| Protein Refseq : | NP_001035111.1 |
| MIM : | 602461 |
| UniProt ID : | P78324 |
Products Types
| ◆ Recombinant Protein | ||
| SIRPA-1388H | Acitve Recombinant Human SIRPA protein(Met1-Arg369), mFc-tagged | +Inquiry |
| SIRPA-721H | Recombinant Human SIRPA Protein | +Inquiry |
| SIRPA-13H | Active Recombinant Human SIRPA Protein, His-tagged | +Inquiry |
| SIRPA-293H | Recombinant Human SIRPA Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
| SIRPA-724H | Recombinant Human SIRPA Protein, IgG1 Fc-tagged | +Inquiry |
| ◆ Lysates | ||
| SIRPA-1005RCL | Recombinant Rat SIRPA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
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09/30/2020
I am thankful for the immense support provided by this protein reagent for my experimental work!
06/14/2020
This protein substance is truly an indispensable tool in my laboratory!
09/03/2019
Its performance is stable and reliable, and the manufacturer's quality control ensures that every experiment runs smoothly.
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