Recombinant Human Sirtuin 4, GST-tagged
Cat.No. : | SIRT4-4879H |
Product Overview : | Full-length recombinant human SIRT4 was expressed in E. coli cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SIRT4-4879H |
Description : | SIRT4 is a member of the sirtuin family of proteins which are homologs to the yeast Sir2 protein. Sirtuin family contain a sirtuin core domain and are grouped into four classes with SIRT4 being a member of class IV. SIRT4 lacks deacetylase activity but has ADP-ribosyltransferase activity. Immunoprecipitation analysis shows that SIRT4 interacts with the mitochondrial enzyme glutamate dehydrogenase, and functional analysis show that SIRT4 ADP-ribosylates and inhibits GDH. |
Applications : | Western Blot |
Molecular Weight : | 62 kDa |
Expression System : | E. coli |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1mM PMSF, 25 % glycerol. |
Purity : | > 70 % |
Concentration : | 0.2 ug/ul |
Sequences : | Full-length |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Signaling events mediated by HDAC Class I |
Gene Name : | SIRT4 sirtuin 4 [ Homo sapiens ] |
Official Symbol : | SIRT4 |
Synonyms : | SIRT4; sirtuin 4; SIR2L4; MGC57437; MGC130046; MGC130047; NAD-dependent ADP-ribosyltransferase sirtuin-4; sir2-like 4; sirtuin type 4; OTTHUMP00000239957; SIR2-like protein 4; sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae); sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 4 |
Gene ID : | 23409 |
mRNA Refseq : | NM_012240 |
Protein Refseq : | NP_036372 |
MIM : | 604482 |
UniProt ID : | Q9Y6E7 |
Chromosome Location : | 12q24.31 |
Function : | NAD binding; NAD+ ADP-ribosyltransferase activity; NAD-dependent protein deacetylase activity; hydrolase activity; metal ion binding; protein binding; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
SIRT4-111H | Recombinant Human SIRT4 Protein, GST-tagged | +Inquiry |
SIRT4-024H | Recombinant Human SIRT4 Protein, GST-tagged | +Inquiry |
SIRT4-8182M | Recombinant Mouse SIRT4 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIRT4-30846TH | Recombinant Human SIRT4 | +Inquiry |
Sirt4-1377M | Recombinant Mouse Sirt4 protein, His-tagged | +Inquiry |
◆ Lysates | ||
SIRT4-1831HCL | Recombinant Human SIRT4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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