Recombinant Human SLAMF7 Protein, Fc-tagged, Alexa Fluor 647 conjugated
Cat.No. : | SLAMF7-186HAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant human SLAMF7/CD319 /CRACC Protein, C-Fc Tag (rh SLAMF7/CD319 Fc Chimera) Ser 23-Met 226 (Accession # AAH27867) was produced in human 293 cells (HEK293). |
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Description : | SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | rh SLAMF7/CD319 Fc Chimera is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 49 kDa. DTT-reduced Protein migrates as 60-67 kDa in SDS-PAGE due to glycosylation. |
N-terminal Sequence Analysis : | Ser 23 |
Endotoxin : | < 1.0 EU/ μg of the rh SLAMF7/CD319 Fc Chimera by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Gene Name : | SLAMF7 SLAM family member 7 [ Homo sapiens ] |
Official Symbol : | SLAMF7 |
Synonyms : | SLAMF7; SLAM family member 7; 19A; CD319; CRACC; CS1; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein; |
Gene ID : | 57823 |
mRNA Refseq : | NM_021181 |
Protein Refseq : | NP_067004 |
MIM : | 606625 |
UniProt ID : | Q9NQ25 |
Products Types
◆ Recombinant Protein | ||
SLAMF7-2692H | Recombinant Human SLAMF7 Protein, His-tagged | +Inquiry |
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Slamf7-5898M | Recombinant Mouse Slamf7 Protein, Myc/DDK-tagged | +Inquiry |
SLAMF7-2323M | Recombinant Mouse SLAMF7 Protein (23-224 aa), His-tagged | +Inquiry |
SLAMF7-449H | Recombinant Human SLAMF7 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
SLAMF7-2378HCL | Recombinant Human SLAMF7 cell lysate | +Inquiry |
SLAMF7-2591MCL | Recombinant Mouse SLAMF7 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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