Recombinant Human SLURP1 Protein (Met1-Leu103), His tagged

• Cat.No.: SLURP1-5036H
• Product Overview: Recombinant human SLURP1 (Met1-Leu103) fused with His tag was expressed in E. coli.

Specification

• Description: Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 13.09 kDa
• Protein Length: Met1-Leu103
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: SLURP1 secreted LY6/PLAUR domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: SLURP1
• Synonyms: SLURP1; secreted LY6/PLAUR domain containing 1; secreted Ly-6/uPAR-related protein 1; ANUP; ARS; ARS component B; ArsB; LY6LS; lymphocyte antigen 6 like secreted; MDM; SLURP-1; ARS (component B) -81/S; anti-neoplastic urinary protein; lymphocyte antigen 6-like secreted; secreted Ly6/uPAR related protein 1
• Gene ID: 57152
• mRNA Refseq: NM_020427
• Protein Refseq: NP_065160
• MIM: 606119
• UniProt ID: P55000