Recombinant Human SMO Protein

• Cat.No.: SMO-28H
• Product Overview: Human SMO full-length ORF (NP_005622.1) recombinant protein without tag.

Specification

• Description: The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 86.4 kDa
• AA Sequence: MAAARPARGPELPLLGLLLLLLLGD PGRGAASSGNATGPGPRSAGGSARR SAAVTGPPPPLSHCGRAAPCEPLRY NVCLGSVLPYGATSTLLAGDSDSQE EAHGKLVLWSGLRNAPRCWAVIQPL LCAVYMPKCENDRVELPSRTLCQAT RGPCAIVERERGWPDFLRCTPDRFP EGCTNEVQNIKFNSSGQCEVPLVRT DNPKSWYEDVEGCGIQCQNPLFTEA EHQDMHSYIAAFGAVTGLCTLFTLA TFVADWRNSNRYPAVILFYVNACFF VGSIGWLAQFMDGARREIVCRADGT MRLGEPTSNETLSCVIIFVIVYYAL MAGVVWFVVLTYAWHTSFKALGTTY QPLSGKTSYFHLLTWSLPFVLTVAI LAVAQVDGDSVSGICFVGYKNYRYR AGFVLAPIGLVLIVGGYFLIRGVMT LFSIKSNHPGLLSEKAASKINETML RLGIFGFLAFGFVLITFSCHFYDFF NQAEWERSFRDYVLCQANVTIGLPT KQPIPDCEIKNRPSLLVEKINLFAM FGTGIAMSTWVWTKATLLIWRRTWC RLTGQSDDEPKRIKKSKMIAKAFSK RHELLQNPGQELSFSMHTVSHDGPV AGLAFDLNEPSADVSSAWAQHVTKM VARRGAILPQDISVTPVATPVPPEE QANLWLVEAEISPELQKRLGRKKKR RKRKKEVCPLAPPPELHPPAPAPST IPRLPQLPRQKCLVAAGAWGAGDSC RQGAWTLVSNPFCPEPSPPQDPFLP SAPAPVAWAHGRRQGLGPIHSRTNL MDTELMDADSDF
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH 8.0 containing 2% glycerol.
• Reconstitution: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.

Gene Information

• Gene Name: SMO
• Official Symbol: SMO smoothened, frizzled class receptor [ Homo sapiens (human) ]
• Synonyms: SMO; smoothened, frizzled class receptor; Gx; CRJS; SMOH; FZD11; smoothened homolog; frizzled family member 11; protein Gx; seven transmembrane helix receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
• Gene ID: 6608
• mRNA Refseq: NM_005631
• Protein Refseq: NP_005622
• MIM: 601500
• UniProt ID: Q99835