Recombinant Human SMYD2, GST-tagged
Cat.No. : | SMYD2-6967H |
Product Overview : | Recombinant full-length human SMYD2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | SMYD2 (also known as SET and MYND domain-containing protein 2) is a member of the SMYD family of protein methyltransferases. SMYD2 is also known as lysine methyltransferase protein 3C (KMT3C). SMYD2 functions to repress transcription by interacting with the Sin3A histone deacetylase complex and performs methylation of Lys36 in histone H3. The exogenous expression of SMYD2 in mouse fibroblasts decreases cell growth. SMYD2 also function as a putative oncogene by methylating p53 and repressing its tumor suppressive function. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~70 kDa |
Protein length : | Full length |
Purity : | >85% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μ |
Gene Name : | SMYD2 SET and MYND domain containing 2 [ Homo sapiens ] |
Official Symbol : | SMYD2 |
Synonyms : | SMYD2; SET and MYND domain containing 2; N-lysine methyltransferase SMYD2; HSKM B; KMT3C; ZMYND14; lysine N-methyltransferase 3C; histone methyltransferase SMYD2; zinc finger, MYND domain containing 14; SET and MYND domain-containing protein 2; HSKM-B; MGC119305; |
Gene ID : | 56950 |
mRNA Refseq : | NM_020197 |
Protein Refseq : | NP_064582 |
MIM : | 610663 |
UniProt ID : | Q9NRG4 |
Chromosome Location : | 1q32.3 |
Pathway : | p53 pathway, organism-specific biosystem; |
Function : | RNA polymerase II core binding; histone methyltransferase activity (H3-K36 specific); metal ion binding; methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltransferase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
SMYD2-8507M | Recombinant Mouse SMYD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Smyd2-5986M | Recombinant Mouse Smyd2 Protein, Myc/DDK-tagged | +Inquiry |
SMYD2-2063H | Recombinant Human SMYD2 Protein, MYC/DDK-tagged | +Inquiry |
SMYD2-019H | Active Recombinant Human SMYD2 Protein, His/SUMO-tagged | +Inquiry |
SMYD2-5289R | Recombinant Rat SMYD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SMYD2-705HCL | Recombinant Human SMYD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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