Recombinant Human SNRNP70 protein

• Cat.No.: SNRNP70-227H
• Product Overview: Recombinant Human SNRNP70 was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Form: U1-snRNP is supplied in 20mM HEPES buffer pH-7.5, 0.01mM EDTA and 0.02% SDS.
• Molecular Mass: Recombinant Human U1-snRNP 68kDa cDNA codes for the 70kDa isoform of the human U1-snRNP 68 protein (lacking 66 internal amino acids outside the known epitope-containing areas) fused to a hexahistidine purification tag.
  The Calculated molecular weight is 44.8 kDa (U1-snRNP 68 displays aberrant electrophoretic mobility leading to an apparent discrepancy between calculated molecular weight and the 55-56 kDa molecular weight determined for this internally shortened molecule by SDS gel electrophoresis).
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: Western-Blot with monoclonal anti-hexa-His-tag antibody & MCTD sera (Mixed Connective Tissue Disease).
• Storage: Store at 4 centigrade if entire vial will be used within 2-4 weeks.
  Store, frozen at -20 centigrade for longer periods of time.
  Avoid multiple freeze-thaw cycles.
• Publication:
  Cohesin regulates alternative splicing (2023)

Gene Information

• Gene Name: SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) [ Homo sapiens ]
• Official Symbol: SNRNP70
• Synonyms: SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); RNPU1Z, RPU1, small nuclear ribonucleoprotein 70kDa (RNP antigen) , SNRP70; U1 small nuclear ribonucleoprotein 70 kDa; Snp1; U1 70K; U1 snRNP 70 kDa; RPU1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K
• Gene ID: 6625
• mRNA Refseq: NM_003089
• Protein Refseq: NP_003080
• MIM: 180740
• UniProt ID: P08621