Recombinant Human SNURF, His-tagged
Cat.No. : | SNURF-5032H |
Product Overview : | Recombinant human SNURF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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Description : | SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5" untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5" UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% glycerol, 1mM DTT. |
Molecular Mass : | 10.8 kDa (94aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMERARDR LHLRRTTEQH VPEVEVQVKR RRTASLSNQE CQLYPRRSQQ QQVPVVDFQA ELRQAFLAET PRGG |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | SNURF SNRPN upstream reading frame [ Homo sapiens (human) ] |
Official Symbol : | SNURF |
Synonyms : | SNURF;SNRPN upstream reading frame protein |
Gene ID : | 8926 |
mRNA Refseq : | NM_005678.3 |
Protein Refseq : | NP_005669.2 |
UniProt ID : | Q9Y675 |
Chromosome Location : | 15q12 |
Pathway : | Coregulation of Androgen receptor activity;Gastric cancer network 2;mRNA processing |
Function : | molecular_function |
Products Types
◆ Recombinant Protein | ||
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SNURF-5651R | Recombinant Rat SNURF Protein | +Inquiry |
SNURF-431H | Recombinant Human SNRPN upstream reading frame, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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