Recombinant Human SNW1, His-tagged
Cat.No. : | SNW1-29295TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 271-536 of Human NCOA62 with an N terminal His tag. Predicted MWt: 32. |
- Specification
- Gene Information
- Related Products
Description : | This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 57 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | DGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVER KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGE ARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENR DISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAG GEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLE ARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLD KFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE |
Gene Name : | SNW1 SNW domain containing 1 [ Homo sapiens ] |
Official Symbol : | SNW1 |
Synonyms : | SNW1; SNW domain containing 1; SKI interacting protein , SKIIP; SNW domain-containing protein 1; Bx42; NCoA 62; Prp45; PRPF45; SKIP; |
Gene ID : | 22938 |
mRNA Refseq : | NM_012245 |
Protein Refseq : | NP_036377 |
MIM : | 603055 |
Uniprot ID : | Q13573 |
Chromosome Location : | 14q22.1-q22.3 |
Pathway : | Delta-Notch Signaling Pathway, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; NICD traffics to nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; |
Function : | Notch binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SNW1-852Z | Recombinant Zebrafish SNW1 | +Inquiry |
◆ Lysates | ||
SNW1-618HCL | Recombinant Human SNW1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket