Description : |
This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
59.6 kDa |
AA Sequence : |
MADEDGEGIHPSAPHRNGGGGGGGG SGLHCAGNGGGGGGGPRVVRIVKSE SGYGFNVRGQVSEGGQLRSINGELY APLQHVSAVLPGGAADRAGVRKGDR ILEVNHVNVEGATHKQVVDLIRAGE KELILTVLSVPPHEADNLDPSDDSL GQSFYDYTEKQAVPISVPRYKHVEQ NGEKFVVYNVYMAGRQLCSKRYREF AILHQNLKREFANFTFPRLPGKWPF SLSEQQLDARRRGLEEYLEKVCSIR VIGESDIMQEFLSESDENYNGVSDV ELRVALPDGTTVTVRVKKNSTTDQV YQAIAAKVGMDSTTVNYFALFEVIS HSFVRKLAPNEFPHKLYIQNYTSAV PGTCLTIRKWLFTTEEEILLNDNDL AVTYFFHQAVDDVKKGYIKAEEKSY QLQKLYEQRKMVMYLNMLRTCEGYN EIIFPHCACDSRRKGHVITAISITH FKLHACTEEGQLENQVIAFEWDEMQ RWDTDEEGMAFCFEYARGEKKPRWV KIFTPYFNYMHECFERVFCELKWRK EEYTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |