Recombinant Human SPINK1 Protein

• Cat.No.: SPINK1-704H
• Product Overview: Recombinant Human SPINK1(Asp24-Cys79) was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
• Source: HEK293 cells
• Species: Human
• Form: 20mM MES, 150mM NaCl, 2mM CaCl2, 1mM DTT, 0.05% Brij35, 10% Glycerol, pH 6.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 7.3 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SPINK1 serine peptidase inhibitor, Kazal type 1 [ Homo sapiens ]
• Official Symbol: SPINK1
• Synonyms: SPINK1; serine peptidase inhibitor, Kazal type 1; serine protease inhibitor, Kazal type 1; pancreatic secretory trypsin inhibitor; PCTT; PSTI; Spink3; TATI; tumor-associated trypsin inhibitor; serine protease inhibitor Kazal-type 1; TCP
• Gene ID: 6690
• mRNA Refseq: NM_003122
• Protein Refseq: NP_003113
• MIM: 167790
• UniProt ID: P00995