Recombinant Human SPTA1 Protein, GST-tagged

• Cat.No.: SPTA1-114H
• Product Overview: Recombinant Human SPTA1 Protein, fused to GST-tag, was expressed in E.coli.

Specification

• Description: This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• Molecular Mass: ~51.3 kDa
• AA Sequence: Kklneasrqqrfntsirdfefwlse aetllamkdqardlasagnllkkhq lleremlaredalkdlntlaedlls sgtfnvdqivkkkdnvnkrflnvqe laaahheklkeayalfqffqdldde eswieeklirvssqdygrdlqgvqn llkkhkrlegelvahepaiqnvldm aeklkdkaavgqeeiqlrlaqfveh weklkelakarglklees
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: SPTA1 spectrin alpha, erythrocytic 1 [ Homo sapiens (human) ]
• Official Symbol: SPTA1
• Synonyms: EL2; HPP; HS3; SPH3; SPTA
• Gene ID: 6708
• mRNA Refseq: NM_003126
• Protein Refseq: NP_003117
• MIM: 182860
• UniProt ID: P02549