Description : |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
59.7 kDa |
AA Sequence : |
MGSNKSKPKDASQRRRSLEPAENVH GAGGGAFPASQTPSKPASADGHRGP SAAFAPAAAEPKLFGGFNSSDTVTS PQRAGPLAGGVTTFVALYDYESRTE TDLSFKKGERLQIVNNTEGDWWLAH SLSTGQTGYIPSNYVAPSDSIQAEE WYFGKITRRESERLLLNAENPRGTF LVRESETTKGAYCLSVSDFDNAKGL NVKHYKIRKLDSGGFYITSRTQFNS LQQLVAYYSKHADGLCHRLTTVCPT SKPQTQGLAKDAWEIPRESLRLEVK LGQGCFGEVWMGTWNGTTRVAIKTL KPGTMSPEAFLQEAQVMKKLRHEKL VQLYAVVSEEPIYIVTEYMSKGSLL DFLKGETGKYLRLPQLVDMAAQIAS GMAYVERMNYVHRDLRAANILVGEN LVCKVADFGLARLIEDNEYTARQGA KFPIKWTAPEAALYGRFTIKSDVWS FGILLTELTTKGRVPYPGMVNREVL DQVERGYRMPCPPECPESLHDLMCQ CWRKEPEERPTFEYLQAFLEDYFTS TEPQYQPGENLTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |