Recombinant Human SSRP1, His-tagged
Cat.No. : | SSRP1-29276TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 274-709 of Human SSRP1 with an N terminal His tag. Predicted MWt: 51 kDa; |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 133 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | ILLFSKDEDISLTLNMNEEEVEKRF EGRLTKNMSGSLYEM VSRVMKALVNRKITVPGNFQGHSGA QCITCSYKASSGL LYPLERGFIYVHKPPVHIRFDEISF VNFARGTTTTRSFDFEIETKQGTQY TFSSIEREEYGKLFDFVNAKKLNIK NRG LKEGMNPSYDEYADSDEDQHDAYLE RMKEEGKIREENA NDSSDDSGEETDESFNPGEEEEDVA EEFDSNASASSSSNE GDSDRDEKKRKQLKKAKMAKDRKSR KKPVEVKKGKDPN APKRPMSAYMLWLNASREKIKSDHP GISITDLSKKAGE IWKGMSKEKKEEWDRKAEDARRDYE KAMKEYEGGRGESSK RDKSKKKKKVKVKMEKKSTPSRGSS SKSSSRQLSESFK SKEFVSSDESSSGENKSKKKRRRSE DSEEEELASTPPS SEDSASGSDE |
Gene Name : | SSRP1 structure specific recognition protein 1 [ Homo sapiens ] |
Official Symbol : | SSRP1 |
Synonyms : | SSRP1; structure specific recognition protein 1; FACT complex subunit SSRP1; facilitates chromatin remodeling 80 kDa subunit; FACT80; |
Gene ID : | 6749 |
mRNA Refseq : | NM_003146 |
Protein Refseq : | NP_003137 |
MIM : | 604328 |
Uniprot ID : | Q08945 |
Chromosome Location : | 11q12 |
Pathway : | Formation and Maturation of mRNA Transcript, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; Gene Expression, organism-specific biosystem; |
Function : | DNA binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SSRP1-4308R | Recombinant Rhesus Macaque SSRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ssrp1-6146M | Recombinant Mouse Ssrp1 Protein, Myc/DDK-tagged | +Inquiry |
SSRP1-5417R | Recombinant Rat SSRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SSRP1-4492R | Recombinant Rhesus monkey SSRP1 Protein, His-tagged | +Inquiry |
SSRP1-5758R | Recombinant Rat SSRP1 Protein | +Inquiry |
◆ Lysates | ||
SSRP1-1456HCL | Recombinant Human SSRP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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