Recombinant Human STAMBP Protein (S2-R424), Tag Free
Cat.No. : | STAMBP-1350S |
Product Overview : | Recombinant Human GG-AMSH(S2-R424 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | S2-R424 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | STAMBP STAM binding protein [ Homo sapiens (human) ] |
Official Symbol : | STAMBP |
Synonyms : | STAMBP; STAM binding protein; STAM-binding protein; AMSH; endosome-associated ubiquitin isopeptidase; associated molecule with the SH3 domain of STAM; MGC126516; MGC126518; |
Gene ID : | 10617 |
mRNA Refseq : | NM_006463 |
Protein Refseq : | NP_006454 |
MIM : | 606247 |
UniProt ID : | O95630 |
Products Types
◆ Recombinant Protein | ||
Stambp-672M | Recombinant Mouse Stambp Protein, His-tagged | +Inquiry |
STAMBP-4323R | Recombinant Rhesus Macaque STAMBP Protein, His (Fc)-Avi-tagged | +Inquiry |
STAMBP-5435R | Recombinant Rat STAMBP Protein, His (Fc)-Avi-tagged | +Inquiry |
Stambp-6159M | Recombinant Mouse Stambp Protein, Myc/DDK-tagged | +Inquiry |
STAMBP-11H | Active Recombinant Human STAMBP Protein (Full Length), N-His-tagged | +Inquiry |
◆ Lysates | ||
STAMBP-1428HCL | Recombinant Human STAMBP 293 Cell Lysate | +Inquiry |
STAMBP-1427HCL | Recombinant Human STAMBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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