Recombinant Human STAR Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: STAR-1396H
• Product Overview: STAR MS Standard C13 and N15-labeled recombinant protein (NP_001007244) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.9 kDa
• AA Sequence: MLLATFKLCAGSSYRHMRNMKGLRQ QAVMAISQELNRRALGGPTPSTWIN QVRRRSSLLGSRLEETLYSDQELAY LQQGEEAMQKALGILSNQEGWKKES QQDNGDKVMSKVVPDVGKVFRLEVV VDQPMERLYEELVERMEAMGEWNPN VKEIKVLQKIGGPRDFVSVRCAKRR GSTCVLAGMATDFGNMPEQKGVIRA EHGPTCMVLHPLAGSPSKTKLTWLL SIDLKGWLPKSIINQVLSQTQVDFA NHLRKRLESHPASEARCTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: STAR steroidogenic acute regulatory protein [ Homo sapiens (human) ]
• Official Symbol: STAR
• Synonyms: STAR; steroidogenic acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein, mitochondrial; StAR; StAR related lipid transfer (START) domain containing 1; STARD1; cholesterol trafficker; START domain containing 1; steroid acute regulatory protein; START domain-containing protein 1; mitochondrial steroid acute regulatory protein; StAR-related lipid transfer (START) domain containing 1
• Gene ID: 6770
• mRNA Refseq: NM_001007243
• Protein Refseq: NP_001007244
• MIM: 600617
• UniProt ID: P49675