Recombinant Human STARD5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: STARD5-678H
• Product Overview: STARD5 MS Standard C13 and N15-labeled recombinant protein (NP_871629) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.8 kDa
• AA Sequence: MDPALAAQMSEAVAEKMLQYRRDTA GWKICREGNGVSVSWRPSVEFPGNL YRGEGIVYGTLEEVWDCVKPAVGGL RVKWDENVTGFEIIQSITDTLCVSR TSTPSAAMKLISPRDFVDLVLVKRY EDGTISSNATHVEHPLCPPKPGFVR GFNHPCGCFCEPLPGEPTKTNLVTF FHTDLSGYLPQNVVDSFFPRSMTRF YANLQKAVKQFHETRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: STARD5 StAR related lipid transfer domain containing 5 [ Homo sapiens (human) ]
• Official Symbol: STARD5
• Synonyms: STARD5; StAR-related lipid transfer (START) domain containing 5; START domain containing 5; stAR-related lipid transfer protein 5; MGC10327; START domain-containing protein 5
• Gene ID: 80765
• mRNA Refseq: NM_181900
• Protein Refseq: NP_871629
• MIM: 607050
• UniProt ID: Q9NSY2