Recombinant Human SUN3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SUN3-3549H
• Product Overview: SUN3 MS Standard C13 and N15-labeled recombinant protein (NP_001025190) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.3 kDa
• AA Sequence: MSGKTKARRAAMFFRRCSEDASGSA SGNALLSEDENPDANGVTRSWKIIL STMLTLTFLLVGLLNHQWLKETDVP QKSRQLYAIIAEYGSRLYKYQARLR MPKEQLELLKKESQNLENNFRQILF LIEQIDVLKALLRDMKDGMDNNHNW NTHGDPVEDPDHTEEVSNLVNYVLK KLREDQVEMADYALKSAGASIIEAG TSESYKNNKAKLYWHGIGFLNHEMP PDIILQPDVYPGKCWAFPGSQGHTL IKLATKIIPTAVTMEHISEKVSPSG NISSAPKEFSVYGITKKCEGEEIFL GQFIYNKTGTTVQTFELQHAVSEYL LCVKLNIFSNWGHPKYTCLYRFRVH GTPGKHITRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SUN3 Sad1 and UNC84 domain containing 3 [ Homo sapiens (human) ]
• Official Symbol: SUN3
• Synonyms: SUN3; Sad1 and UNC84 domain containing 3; Sad1 and UNC84 domain containing 1, SUNC1; SUN domain-containing protein 3; MGC33329; Sad1 and UNC84 domain containing 1; sad1/unc-84 domain-containing protein 1; SUNC1
• Gene ID: 256979
• mRNA Refseq: NM_001030019
• Protein Refseq: NP_001025190
• MIM: 618984
• UniProt ID: Q8TAQ9