Recombinant Human TADA2A Protein, His-tagged

• Cat.No.: TADA2A-126H
• Product Overview: Recombinant human TADA2A protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 35.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: transcriptional adaptor 2A [ Homo sapiens ]
• Official Symbol: TADA2A
• Synonyms: ADA2; ADA2A; hADA2; KL04P; TADA2L
• Gene ID: 6871
• mRNA Refseq: NM_001488.4
• Protein Refseq: NP_001479.4
• MIM: 602276
• UniProt ID: O75478