Recombinant Human TARDBP, GST-tagged
Cat.No. : | TARDBP-4735H |
Product Overview : | Recombinant Human TARDBP(1 a.a. - 260 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 54.34 kDa |
AA Sequence : | MSEYIRVTEDENDEPIEIPSEDDGT VLLSTVTAQFPGACGLRYRNPVSQC MRGVRLVEGILHAPDAGWGNLVYVV NYPKDNKRKMDETDASSAVKVKRAV QKTSDLIVLGLPWKTTEQDLKEYFS TFGEVLMVQVKKDLKTGHSKGFGFV RFTEYETQVKVMSQRHMIDGRWCDC KLPNSKQSQDEPLRSRKVFVGRCTE DMTEDELREFFSQYGDVMDVFIPKP FRAFAFVTFADDQIAQSLCGEDLII KGISVHISNA |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | TARDBP TAR DNA binding protein [ Homo sapiens (human) ] |
Official Symbol : | TARDBP |
Synonyms : | TARDBP; TDP-43; TAR DNA binding protein; ASL 10; TAR DNA-binding protein 43; TDP43; TAR DNA-binding protein 43; OTTHUMP00000002173; TRA DNA-binding protein-43 |
Gene ID : | 23435 |
mRNA Refseq : | NM_007375 |
Protein Refseq : | NP_003140 |
MIM : | 605078 |
UniProt ID : | Q13148 |
Chromosome Location : | 1p36.22 |
Function : | RNA binding; double-stranded DNA binding; mRNA 3'-UTR binding; nucleotide binding; protein binding; sequence-specific DNA binding transcription factor activity |
Products Types
◆ Recombinant Protein | ||
TARDBP-41H | Recombinant Human TARDBP Protein (Full length), N-GST-tagged | +Inquiry |
TARDBP-2192H | Recombinant Human TARDBP Protein (1-396 aa), His-tagged | +Inquiry |
TARDBP-22H | Recombinant Human TARDBP Protein | +Inquiry |
Tardbp-6294M | Recombinant Mouse Tardbp Protein, Myc/DDK-tagged | +Inquiry |
TARDBP-5776H | Recombinant Human TARDBP Protein (Ser104-Pro262), N-His tagged | +Inquiry |
◆ Lysates | ||
TARDBP-1251HCL | Recombinant Human TARDBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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