| Description : |
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
57.5 kDa |
| AA Sequence : |
MADADEGFGLAHTPLEPDAKDLPCD SKPESALGAPSKSPSSPQAAFTQQG MEGIKVFLHERELWLKFHEVGTEMI ITKAGRRMFPSYKVKVTGLNPKTKY ILLMDIVPADDHRYKFADNKWSVTG KAEPAMPGRLYVHPDSPATGAHWMR QLVSFQKLKLTNNHLDPFGHIILNS MHKYQPRLHIVKADENNGFGSKNTA FCTHVFPETAFIAVTSYQNHKITQL KIENNPFAKGFRGSDDMELHRMSRM QSKEYPVVPRSTVRQKVASNHSPFS SESRALSTSSNLGSQYQCENGVSGP SQDLLPPPNPYPLPQEHSQIYHCTK RKEEECSTTDHPYKKPYMETSPSEE DSFYRSSYPQQQGLGASYRTESAQR QACMYASSAPPSEPVPSLEDISCNT WPSMPSYSSCTVTTVQPMDRLPYQH FSAHFTSGPLVPRLAGMANHGSPQL GEGMFQHQTSVAHQPVVRQCGPQTG LQSPGTLQPPEFLYSHGVPRTLSPH QYHSVHGVGMVPEWSDNSTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
