Recombinant Human TCF7 Protein, His-tagged
Cat.No. : | TCF7-119H |
Product Overview : | Recombinant Human TCF7 Protein, fused to His-tag, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Supplied as a 0.2 μm filtered solution in 25mM Tris, 0.3M NaCl, 0.1 mM EDTA, 50% glycerol, pH 7.4. |
Molecular Mass : | ~45.2 kDa |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMASMT GGQQMGRGSMPQLDSGGGGAGGGDD LGAPDELLAFQDEGEEQDDKSRDSA AGPERDLAELKSSLVNESEGAAGGA GIPGVPGAGAGARGEAEALGREHAA QRLFPDKLPEPLEDGLKAPECTSGM YKETVYSAFNLLMHYPPPSGAGQHP QPQPPLHKANQPPHGVPQLSLYEHF NSPHPTPAPADISQKQVHRPLQTPD LSGFYSLTSGSMGQLPHTVSWFTHP SLMLGSGVPGHPAAIPHPAIVPPSG KQELQPFDRNLKTQAESKAEKEAKK PTIKKPLNAFMLYMKEMRAKVIAEC TLKESAAINQILGRRWHALSREEQA KYYELARKERQLHMQLYPGWSARDN YGKKKRRSREKHQESTTETNWPREL KDGNGQESLSMSSSSSPA |
Endotoxin : | <1EU/ug |
Purity : | >90% |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 1 mg/ml |
Gene Name : | TCF7 transcription factor 7 [ Homo sapiens (human) ] |
Official Symbol : | TCF7 |
Synonyms : | TCF-1 |
Gene ID : | 6932 |
mRNA Refseq : | NM_001134851 |
Protein Refseq : | NP_001128323 |
MIM : | 189908 |
UniProt ID : | P36402 |
Products Types
◆ Recombinant Protein | ||
TCF7-15H | Recombinant Human TCF7 Protein, GST-tagged | +Inquiry |
TCF7-9082M | Recombinant Mouse TCF7 Protein, His (Fc)-Avi-tagged | +Inquiry |
TCF7-4921H | Recombinant Human TCF7 protein(1-384aa), His&Myc-tagged | +Inquiry |
TCF7-120M | Recombinant Mouse TCF7 Protein, His-tagged | +Inquiry |
TCF7-2043Z | Recombinant Zebrafish TCF7 | +Inquiry |
◆ Lysates | ||
TCF7-1753HCL | Recombinant Human TCF7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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