Recombinant Human TDO2, GST-tagged
Cat.No. : | TDO2-825H |
Product Overview : | Full-length recombinant human TDO2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~69 kDa |
Protein length : | Full Length |
Purity : | >95% |
Applications : | Western Blot |
Stability : | 1 yr at -70ºC from date of shipment. |
Storage : | Store product at –70ºC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | TDO2 tryptophan 2,3-dioxygenase [ Homo sapiens (human) ] |
Official Symbol : | TDO2 |
Synonyms : | TDO; TPH2; TRPO; TDO2; tryptophan 2,3-dioxygenase; TO; tryptophanase; tryptophan oxygenase; tryptophan pyrrolase; tryptamin 2,3-dioxygenase; EC 1.13.11.11 |
Gene ID : | 6999 |
mRNA Refseq : | NM_005651 |
Protein Refseq : | NP_005642 |
MIM : | 191070 |
UniProt ID : | P48775 |
Chromosome Location : | 4q31-q32 |
Pathway : | Metabolic pathways; Tryptophan metabolism; Metabolism of amino acids and derivatives |
Function : | amino acid binding; heme binding; metal ion binding; oxidoreductase activity; oxygen binding; oxygen binding; tryptopha 2,3-dioxygenase activity |
Products Types
◆ Recombinant Protein | ||
TDO2-1958R | Recombinant Rat TDO2 Protein (1-406 aa), His-SUMO-tagged | +Inquiry |
TDO2-9103M | Recombinant Mouse TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDO2-1536M | Recombinant Mouse TDO2 Protein (1-406 aa), His-tagged | +Inquiry |
TDO2-4170H | Recombinant Human TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tdo2-6347M | Recombinant Mouse Tdo2 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
TDO2-1156HCL | Recombinant Human TDO2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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