Recombinant Human TFPI protein, His/GST-tagged
Cat.No. : | TFPI-107H |
Product Overview : | Recombinant Human TFPI(Asp29~Cys251) fused with His/GST tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. |
Source : | E. coli |
Species : | Human |
Tag : | His/GST |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
Molecular Mass : | 57.6kDa |
Protein length : | Asp29~Cys251 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) [ Homo sapiens ] |
Official Symbol : | TFPI |
Synonyms : | TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); LACI; tissue factor pathway inhibitor; EPI; extrinsic pathway inhibitor; TFI; TFPI1; anti-convertin; |
Gene ID : | 7035 |
mRNA Refseq : | NM_001032281 |
Protein Refseq : | NP_001027452 |
MIM : | 152310 |
UniProt ID : | P10646 |
Products Types
◆ Recombinant Protein | ||
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TFPI-751H | Recombinant Human TFPI Protein, Biotinylated | +Inquiry |
TFPI-707H | Recombinant Human TFPI Protein, MYC/DDK-tagged | +Inquiry |
TFPI-1246H | Recombinant Human TFPI Protein, His-tagged | +Inquiry |
Tfpi-6383M | Recombinant Mouse Tfpi Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
TFPI-2746HCL | Recombinant Human TFPI cell lysate | +Inquiry |
TFPI-2843MCL | Recombinant Mouse TFPI cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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