| Description : |
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
88.6 kDa |
| AA Sequence : |
MERLWGLFQRAQQLSPRSSQTVYQR VEGPRKGHLEEEEEDGEEGAETLAH FCPMELRGPEPLGSRPRQPNLIPWA AAGRRAAPYLVLTALLIFTGAFLLG YVAFRGSCQACGDSVLVVSEDVNYE PDLDFHQGRLYWSDLQAMFLQFLGE GRLEDTIRQTSLRERVAGSAGMAAL TQDIRAALSRQKLDHVWTDTHYVGL QFPDPAHPNTLHWVDEAGKVGEQLP LEDPDVYCPYSAIGNVTGELVYAHY GRPEDLQDLRARGVDPVGRLLLVRV GVISFAQKVTNAQDFGAQGVLIYPE PADFSQDPPKPSLSSQQAVYGHVHL GTGDPYTPGFPSFNQTQFPPVASSG LPSIPAQPISADIASRLLRKLKGPV APQEWQGSLLGSPYHLGPGPRLRLV VNNHRTSTPINNIFGCIEGRSEPDH YVVIGAQRDAWGPGAAKSAVGTAIL LELVRTFSSMVSNGFRPRRSLLFIS WDGGDFGSVGSTEWLEGYLSVLHLK AVVYVSLDNAVLGDDKFHAKTSPLL TSLIESVLKQVDSPNHSGQTLYEQV VFTNPSWDAEVIRPLPMDSSAYSFT AFVGVPAVEFSFMEDDQAYPFLHTK EDTYENLHKVLQGRLPAVAQAVAQL AGQLLIRLSHDRLLPLDFGRYGDVV LRHIGNLNEFSGDLKARGLTLQWVY SARGDYIRAAEKLRQEIYSSEERDE RLTRMYNVRIMRVEFYFLSQYVSPA DSPFRHIFMGRGDHTLGALLDHLRL LRSNSSGTPGATSSTGFQESRFRRQ LALLTWTLQGAANALSGDVWNIDNN FTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
