Recombinant Human TGFB1 Protein, Fc-tagged
Cat.No. : | TGFB1-04H |
Product Overview : | Recombinant Human TGFB1 Protein, fused to Fc-tag was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Liquid |
AA Sequence : | ALDTNYCFSSTEKNCCVRQLYIDFR KDLGWKWIHEPKGYHANFCLGPCPY IWSLDTQYSKVLALYNQHNPGASAA PCCVPQALEPLPIVYYVGRKPKVEQ LSNMIVRSCKCSLEVLFQGGGGGSD KTHTCPPCPAPELLGGPSVFLFPPK PKDTLMISRTPEVTCVVVDVSHEDP EVKFNWYVDGVEVHNAKTKPREEQY NSTYRVVSVLTVLHQDWLNGKEYKC KVSNKALPAPIEKTISKAKGQPREP QVYTLPPSREEMTKNQVSLTCLVKG FYPSDIAVEWESNGQPENNYKTTPP VLDSDGSFFLYSKLTVDKSRWQQGN VFSCSVMHEALHNHYTQKSLSLSPG K* |
Purity : | >90% determined by SDS-PAGE (Reduced). |
Storage : | Store at -20 centigrade to -80 centigrade. |
Storage Buffer : | PBS, pH 6.8 |
Gene Name : | TGFB1 transforming growth factor beta 1 [ Homo sapiens (human) ] |
Official Symbol : | TGFB1 |
Synonyms : | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
Gene ID : | 7040 |
mRNA Refseq : | NM_000660.7 |
Protein Refseq : | NP_000651.3 |
MIM : | 190180 |
UniProt ID : | P01137 |
Products Types
◆ Recombinant Protein | ||
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TGFB1-299H | Recombinant Active Human TGFB1 Protein, His-tagged(C-ter) | +Inquiry |
Tgfb1-1251M | Recombinant Mouse Tgfb1 Protein, His-tagged | +Inquiry |
TGFB1-829B | Recombinant Bovine TGFB1 Protein (279-390 aa), His-tagged | +Inquiry |
◆ Native Protein | ||
TGFB1-21H | Active Native Human TGF- β1 | +Inquiry |
◆ Lysates | ||
TGFB1-803RCL | Recombinant Rat TGFB1 cell lysate | +Inquiry |
TGFB1-001MCL | Recombinant Mouse TGFB1 cell lysate | +Inquiry |
TGFB1-2662HCL | Recombinant Human TGFB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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