Recombinant Human TGFB3 protein, Avi-tagged, Biotinylated

• Cat.No.: TGFB3-600HB
• Product Overview: Biotinylated Human Latent TGFB3, Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 301 - Ser 412 (Accession # P10600-1).

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
• Source: HEK293
• Species: Human
• Tag: Avi
• Predicted N Terminal: Ala 301
• Form: Please contact us for detailed information.
• Molecular Mass: This protein carries an Avi tag at the C-terminus.
  The protein has a calculated MW of 14.4 kDa.
• Protein length: Ala 301 - Ser 412
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20°C to -70°C for 12 months in lyophilized state;
  -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: TGFB3 transforming growth factor beta 3 [ Homo sapiens (human) ]
• Official Symbol: TGFB3
• Synonyms: TGFB3; ARVD; TGF-beta3
• Gene ID: 7043
• mRNA Refseq: NM_001329938.2
• Protein Refseq: NP_001316867.1
• MIM: 190230
• UniProt ID: P10600