Recombinant Human TGFBR2 Protein, 23-166aa, C-hIgG-His tagged
Cat.No. : | TGFBR2-05H |
Product Overview : | Recombinant human TGFBR2 (23-166aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | TGFBR2, as known as TGF-beta receptor type-2 isoform B, is a member of the serine and threonine protein kinase family and the TGF beta receptor subfamily. The type-2 receptor binds TGF-beta1 and TGF-beta3 with high affinity, and TGF-beta2 with a much lower affinity. It forms a heterodimeric complex with type1 receptor and is essential for signal transduction. Also, this protein may play an important role in TGF-beta2 binding and signaling in cells lacking TGFBR3. |
Source : | Insect cells |
Species : | Human |
Tag : | C-hIgG-His |
Protein length : | 23-166aa |
Form : | Liquid |
Bio-activity : | Measured by its binding ability in a functional ELISA with Human TGF-beta3. The ED50 range ≤ 1 μg/mL. |
Molecular Mass : | 43.3 kDa (383aa) |
AA Sequence : | TIPPHVQKSVNNDMIVTDNNGAVKF PQLCKFCDVRFSTCDNQKSCMSNCS ITSICEKPQEVCVAVWRKNDENITL ETVCHDPKLPYHDFILEDAASPKCI MKEKKKPGETFFMCSCSSDECNDNI IFSEEYNTSNPDLLLVIFQ |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 95% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Notes : | For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
References : | 1. Wrana JL., et al. (1992) Cell 71:1003-1014. 2. Halper B., et al. (2015) Exerc. Immunol. Rev. 21:154-163. |
Gene Name : | TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens (human) ] |
Official Symbol : | TGFBR2 |
Synonyms : | TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII; |
Gene ID : | 7048 |
mRNA Refseq : | NM_003242 |
Protein Refseq : | NP_003233 |
MIM : | 190182 |
UniProt ID : | P37173 |
Products Types
◆ Recombinant Protein | ||
TGFBR2-2765H | Recombinant Human TGFBR2 Protein, His-tagged | +Inquiry |
TGFBR2-377H | Active Recombinant Human TGFBR2 protein(Met1-Gln166), His-tagged | +Inquiry |
TGFBR2-703H | Recombinant Human TGFBR2 Protein, MYC/DDK-tagged | +Inquiry |
Tgfbr2-8722R | Active Recombinant Rat Tgfbr2 protein(Met1-Gln166), hFc-tagged | +Inquiry |
TGFBR2-304H | Recombinant Human TGFBR2 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
TGFBR2-1374RCL | Recombinant Rat TGFBR2 cell lysate | +Inquiry |
TGFBR2-1291CCL | Recombinant Cynomolgus TGFBR2 cell lysate | +Inquiry |
TGFBR2-2842HCL | Recombinant Human TGFBR2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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