| Description : |
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
77.1 kDa |
| AA Sequence : |
MAEELVLERCDLELETNGRDHHTAD LCREKLVVRRGQPFWLTLHFEGRNY EASVDSLTFSVVTGPAPSQEAGTKA RFPLRDAVEEGDWTATVVDQQDCTL SLQLTTPANAPIGLYRLSLEASTGY QGSSFVLGHFILLFNAWCPADAVYL DSEEERQEYVLTQQGFIYQGSAKFI KNIPWNFGQFEDGILDICLILLDVN PKFLKNAGRDCSRRSSPVYVGRVVS GMVNCNDDQGVLLGRWDNNYGDGVS PMSWIGSVDILRRWKNHGCQRVKYG QCWVFAAVACTVLRCLGIPTRVVTN YNSAHDQNSNLLIEYFRNEFGEIQG DKSEMIWNFHCWVESWMTRPDLQPG YEGWQALDPTPQEKSEGTYCCGPVP VRAIKEGDLSTKYDAPFVFAEVNAD VVDWIQQDDGSVHKSINRSLIVGLK ISTKSVGRDEREDITHTYKYPEGSS EEREAFTRANHLNKLAEKEETGMAM RIRVGQSMNMGSDFDVFAHITNNTA EEYVCRLLLCARTVSYNGILGPECG TKYLLNLNLEPFSEKSVPLCILYEK YRDCLTESNLIKVRALLVEPVINSY LLAERDLYLENPEIKIRILGEPKQK RKLVAEVSLQNPLPVALEGCTFTVE GAGLTEEQKTVEIPDPVEAGEEVKV RMDLLPLHMGLHKLVVNFESDKLKA VKGFRNVIIGPATRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
