Recombinant Human THNSL2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: THNSL2-4671H
• Product Overview: THNSL2 MS Standard C13 and N15-labeled recombinant protein (NP_060741) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.9 kDa
• AA Sequence: MWYVSTRGVAPRVNFEGALFSGYAP DGGLFMPEELPQLDRGTLCQWSTLS YPGLVKELCALFIGSELLPKDELND LIDRAFSRFRHREVVHLSRLRNGLN VLELWHGVTYAFKDLSLSCTTQFLQ YFLEKREKHVTVVVGTSGDTGSAAI ESVQGAKNMDIIVLLPKGHCTKIQE LQMTTVLKQNVHVFGVEGNSDELDE PIKTVFADVAFVKKHNLMSLNSINW SRVLVQMAHHFFAYFQCTPSLDTHP LPLVEVVVPTGAAGNLAAGYIAQKI GLPIRLVVAVNRNDIIHRTVQQGDF SLSEAVKSTLASAMDIQVPYNMERV FWLLSGSDSQVTRALMEQFERTQSV NLPKELHSKLSEAVTSVSVSDEAIT QTMGRCWDENQYLLCPHSAVAVNYH YQQIDRQQPSTPRCCLAPASAAKFP EAVLAAGLTPETPAEIVALEHKETR CTLMRRGDNWMLMLRDTIEDLSRQW RSHALNTSQTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: THNSL2 threonine synthase like 2 [ Homo sapiens (human) ]
• Official Symbol: THNSL2
• Synonyms: THNSL2; threonine synthase-like 2 (S. cerevisiae); threonine synthase-like 2; FLJ10916; secreted osteoclastogenic factor of activated T cells; secreted osteoclastogenic factor of activated T-cells; THS2; TSH2; SOFAT; FLJ35504
• Gene ID: 55258
• mRNA Refseq: NM_018271
• Protein Refseq: NP_060741
• MIM: 611261
• UniProt ID: Q86YJ6