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Recombinant Human TMC6 Protein, GST-tagged

Cat.No. : TMC6-4048H
Product Overview : Human EVER1 full-length ORF ( AAH35648, 1 a.a. - 444 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 74.58 kDa
AA Sequence : MAHSFGESYRVGSTSGIHAITVFCS WDYKVTQKRASRLQQDNIRTRLKEL LAEWQLRHSPRSVCGRLRQAAVLGL VWLLCLGTALGCAVAVHVFSEFMIQ SPEAAGQEAVLLVLPLVVGLLNLGA PYLCRVLAALEPHDSPVLEVYVAIC RNLILKLAILGTLCYHWLGRRVGVL QGQCWEDFVGQELYRFLVMDFVLML LDTLFGELVWRIISEKKLKRRRKPE FDIARNVLELIYGQTLTWLGVLFSP LLPAVQIIKLLLVFYVKKTSLLANC QAPRRPWLASHMSTVFLTLLCFPAF LGAAVFLCYAVWQVKPSSTCGPFRT LDTMYEAGRVWVRHLEAAGPRVSWL PWVHRYLMENTFFVFLVSALLLAVI YLNIQVVRGQRKVICLLKEQISNEG EDKIFLINKLHSIYERKEREERSRV GTTEEAAAPPALLTDEQDA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : TMC6 transmembrane channel-like 6 [ Homo sapiens ]
Official Symbol : TMC6
Synonyms : TMC6; transmembrane channel-like 6; epidermodysplasia verruciformis 1 , EVER1; transmembrane channel-like protein 6; EVIN1; LAK 4P; protein LAK-4; epidermodysplasia verruciformis 1; expressed in activated T/LAK lymphocytes; epidermodysplasia verruciformis protein 1; EV1; EVER1; LAK-4P; FLJ17776;
Gene ID : 11322
mRNA Refseq : NM_001127198
Protein Refseq : NP_001120670
MIM : 605828
UniProt ID : Q7Z403

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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