Recombinant Human TMIE Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TMIE-4586H
• Product Overview: TMIE MS Standard C13 and N15-labeled recombinant protein (NP_671729) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 17.1 kDa
• AA Sequence: MAGWPGAGPLCVLGGAALGVCLAGV AGQLVEPSTAPPKPKPPPLTKETVV FWDMRLWHVVGIFSLFVLSIIITLC CVFNCRVPRTRKEIEARYLQRKAAK MYTDKLETVPPLNELTEVPGEDKKK KKKKKDSVDTVAIKVEEDEKNEAKK KKGEKTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TMIE transmembrane inner ear [ Homo sapiens (human) ]
• Official Symbol: TMIE
• Synonyms: TMIE; transmembrane inner ear; deafness, autosomal recessive 6, DFNB6; transmembrane inner ear expressed protein; transmembrane inner ear protein; DFNB6
• Gene ID: 259236
• mRNA Refseq: NM_147196
• Protein Refseq: NP_671729
• MIM: 607237
• UniProt ID: Q8NEW7