Recombinant Human TMIGD2 protein, Fc-tagged
Cat.No. : | TMIGD2-568H |
Product Overview : | Recombinant Human TMIGD2 (Leu23-Gly150) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Leu23 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 40.6 kDa. As a result of glycosylation, the protein migrates as 45-60 kDa under reducing (R) condition, and 90-120 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | Leu23-Gly150 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | TMIGD2 |
Official Symbol : | TMIGD2 |
Synonyms : | IGPR1; IGPR-1 |
Gene ID : | 126259 |
mRNA Refseq : | NM_144615.2 |
Protein Refseq : | NP_653216.2 |
MIM : | 614715 |
UniProt ID : | Q96BF3 |
Products Types
◆ Recombinant Protein | ||
TMIGD2-135H | Recombinant Human TMIGD2 Protein, Fc-tagged | +Inquiry |
TMIGD2-1146H | Active Recombinant Human TMIGD2 protein, Fc-tagged | +Inquiry |
TMIGD2-567H | Active Recombinant Human TMIGD2, Fc-tagged, Biotinylated | +Inquiry |
TMIGD2-569H | Active Recombinant Human TMIGD2 protein, His-tagged | +Inquiry |
TMIGD2-271H | Recombinant Human TMIGD2 protein, His-tagged | +Inquiry |
◆ Lysates | ||
TMIGD2-919HCL | Recombinant Human TMIGD2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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